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(2014) Clinical and biochemical correlates of serum l-ergothioneine concentrations in community-dwelling middle-aged and older adults
The following primary antibodies were used (Dilution, Supplier, Clone, cat#, RRID): ACC (1:1000, Cell Signaling, C83B10, #3676, AB_2219397), pACC Ser79 (1:1000, Cell Signaling, #3661, AB_330337), cleaved Caspase-3 Asp175 (1:1000, Cell Signaling, #9664, AB_2070042), GAPDH (1:200, DSHB, 2G7, #DSHB-hGAPDH-2G7), IDO1 (1:1000, Cell Signaling, D5J4E, #86630, AB_2636818), LDHA (1:1000, Cell Signaling, C4B5, #3582, AB_2066887), LDHB (1:5000, Proteintech, #14824-1-AP, AB_2134953), p4E-BP1 Ser65 (1:500, Santa Cruz, 62.Ser 65, #sc-293124, AB_2943677), p4E-BP1 Thr37/46 (1:1000, Cell signaling, 236B4, #2855, AB_560835), Vinculin (1:1000, Sigma, hVIN-1, # V9131, AB_477629)
By neutralizing free radicals within the mitochondria, glutathione may help support more consistent energy levels throughout the day
FDA Drugs@FDA database
However, excessive accumulation of ROS can be detrimental to the body's function
