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When the prostate is quite large, perhaps 80 grams or higher, Dr

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doi: 10.1002/hep.20035 261 AsklingJForedCBaecklundEBrandtLBacklinCEkbomAet al

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The ABEmax editor achieved 30% DNA editing, 40% reduction in PCSK9, and 20% reduction in LDL-C, 102 while the ABE8.8 editor achieved 66% DNA editing, as well as 90% and 60% reduction in PCSK9 and LDL-C, respectively, 103 with minimal off-target effects observed in both studies