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[DOI] [PubMed] [Google Scholar] 26.Costerton J.W., Irvin R.T

Secondly, it is imperative to minimize genotoxic risk by incorporating base and prime editors that circumvent double-strand breaks, utilizing transient delivery formats (such as RNPs, self-inactivating vectors, and split-intein systems), and conducting thorough, unbiased genome- and transcriptome-wide off-target profiling within preclinical packages (233)

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In the BEGONE trial, high-risk obese patients with a history of precancerous colonic polyps or colon cancer participated in a bean-enriched dietary intervention

Am J Phys 273: E226E230, 1997