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This metabolic pathway is considered the main biosynthetic process to produce AsA in plants and to date is the best characterized (Wheeler et al., 1998

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In general, under physiological conditions, substances can cross the BBB through five pathways, including passive diffusion, carrier-mediated transport, adsorptive-mediated transcytosis, adsorptive-mediated transcytosis, and efflux pumps[31, 32] (Fig

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