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Sekhar, Rajagopal V., et al

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The BSO induced experimental mice showed significantly decreased GSH, CAT (catalase), SOD and GPx concentrations, while in the control and sham groups, all the values remained normal

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Researchers introduced a ketone functional group into the erastin structure to obtain the carbonyl analog imidazole ketone erastin (IKE), which is more effective at inducing ferroptosis [128]
