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The perturbation of cellular glutathione homeostasis was achieved by exposing hepatocytes to H 2 O 2 , which is a well-established method of inducing intracellular glutathione imbalance

Thus, they simultaneously work as a checkpoint inhibitor, unleashing the power of T-cell activity, especially on CD8 + T cells [11, 36, 45]

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Recently, in the bile duct ligation-induced liver cirrhosis (Sever et al., 2019), no portal hypertension development and reversal of the already preexisting portal hypertension to normal values (Sever et al., 2019) have become possible

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