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This buffering mechanism is particularly important for the oxidation of pyruvate and -ketoglutarate [60]

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Glucose induced-AKT/mTOR activation accelerates glycolysis and promotes cell survival in acute myeloid leukemia
A., Oudshoorn, A., & Ketting, D

A high TMAO level is related to both major adverse cardiovascular risk (RR = 2.05
