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In contrast, FRs, characterized by high affinity but low capacity, selectively mediate folate endocytosis in certain tissues

the impact of metabolic status of glandular epithelial cells on auto-immunogenicity

Presumably this choice reflects relative ease of administration to animals rather than attempted mimicry of a route most appropriate for administration of a dietary compound or matrix to humans
doi: 10.1038/s41467-019-09234-6

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