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doi:10.1001/jama.2013.280490. 11

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It should be noted that uptake of Se into the brain compartment without a balanced Se-discharge mechanism could finally lead to local, brain-compartment related Se-overexposure

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Supplementary material The Supplementary Material for this article can be found online at: References Akiyama S., Fukuda S., Steinberg J

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Targeting macrophagic SHP2 for ameliorating osteoarthritis via TLR signaling

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Figure 3 3.2 Anticancer mechanisms of carotenoids 3.2.1 Pro-oxidant and antioxidant balance Carotenoids are a class of strong antioxidants that scavenge free radicals and reduce DNA damage from oxidative stress, thereby preventing genetic mutations and cancerous lesions ( 3.2.2 Immunomodulatory effect Carotenoids also exert anticancer effects through immunomodulation

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