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The neuroendocrine phenotype emerges at least in part through suppression of AR signaling as the latter increases the expression of the neuronal transcription factor BRN2 [28]
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Thus, subsequent metabolomic analysis was constrained to a comparison between D-7 and 7.2 Gy D8 as the main response to radiation exposure
This discrepancy may be caused by the poor inhibition of VEGFR inhibition on glucose metabolism or the lack of biomarkers to predict GLS inhibitory response in tumor cells
