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In the present hypothesis article, we surmise that COVID-19 sequelae, including the ME/CFS, may be caused by ANG II-inflicted fragmentation of biological barriers with subsequent microbial and/or lipopolysaccharide (LPS) translocation from the GI tract into various tissues, including the central nervous system (CNS)

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Phosphorylation is considered as an important PTM of Tau as it is implicated in both physiological and pathological states