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Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjgrens Syndrome According to Ancestry

Values represent means SEM ( n = 1016/genotype/diet)

824 This unusual enzyme methylates and cyclizes FPP to the 16-carbon presodorifenyl diphosphate (PSPP, 404 ), which can be converted into a variety of C16 terpenoid scaffolds such as 405407 (Figure 102B)

Antibody titer was determined as the highest dilution factor for each mouse with a higher OD value than background, where the background is the mean absorbance of mice given NaCl plus 5x the standard error of the mean of the same observations

Nonpharmacologic treatment options with published evidence of efficacy in patients with CIPN include chemotherapy dose reduction, discontinuation of the offending chemotherapeutic agent(s), acupuncture, avoiding cold temperatures/maintaining warmth, physical activity, and massaging affected areas ( TABLE 3 )