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Knockdown of HIF-1 significantly increases intracellular ROS and apoptosis levels (Xu, 2018), likely through the upregulation of anti-apoptotic factors or modulation of metabolic pathways

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[DOI] [PubMed] [Google Scholar] 250.Ota S., Morita A., Ohnuki S., Hirata A., Sekida S., Okuda K., Ohya Y., Kawano S