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Microbiology 151:219231
Di Marino et al

Conclusion Glutathione is commonly referred to as the most significant antioxidant of the body

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We have reviewed the mechanism of the Trx and glutathione antioxidant systems, and the roles of these two antioxidant systems in melanogenesis, suggesting that antioxidants have the potential to act as depigmenting agents for the treatment of human hyperpigmentation disorders