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Drug Resistance Update 73 , 101053 (2024)

GSS gene mutations can severely decrease glutathione levels, leading to a deficiency disease

Ziauddeen N, Gurdasani D, OHara ME, Hastie C, Roderick P, Yao G, et al

This phenomenon is likely due to the anti-inflammatory effects of ferroptosis inhibitors, which target OC-STAMP through the inflammation-related RANKL pathway [30, 31], consequently decreasing the expression of OC-STAMP

Mohammadi, and C
