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[78] reported that fisetin can ameliorate type 2 diabetes-related vascular aging by targeting the PI3K/Akt/Bcl-2/Bcl-xl axis, promoting apoptosis of senescent endothelial cells, suppressing SASP factors, and enhancing the therapeutic efficacy of metformin, though direct dose equivalence and mechanistic comparisons were not established

Note: Control group (Glu: n = 9

1 capsule a day with or without food, or as directed by your healthcare practitioner

Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, et al

Necroptosis in cancer: Insight from epigenetic, post-transcriptional and post-translational modifications