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The initial indication that G0S2 was involved in lipolysis was from studies showing that G0S2 mRNA expression is highest in WAT and BAT, upregulated during adipocyte differentiation (51), and a peroxisome proliferator-activated receptor (PPAR) target gene

It is a natural substance produced by the liver and is also found in various fruits, vegetables, and meat

We demonstrated that TrkB signalling in these neurons is essential to maintain normal locomotor behaviour consistent with the initial hyperkinetic symptoms of HD and suggested that TrkB signalling deficiency may contribute effectively to HD motor symptoms 13

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Shi Z, et al
