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Advances in Neural Information Processing Systems , 2017 , 30

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3.3 Intestinal microbial regulation of the neuroimmune axis represents a pivotal driver of colitis pathogenesis In the complex intestinal microenvironment, innate lymphoid cells (ILCs) and neurons form an intricate neuro-immune regulatory network that dynamically coordinates immune defense and tissue homeostasis

The peptide upregulates growth factor receptors, including VEGF, EGF, and FGF receptors, promoting angiogenesis and new blood vessel formation at injury sites