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There are three major catabolic routes that produce 2-ketoadipic acid

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Actyl-L-carnitine (ALCAR) : privilgier pour le soutien cognitif (traverse la barrire hmato-encphalique) Propionyl-L-carnitine : cible la circulation sanguine D-carnitine : inactive et mme contre-productive ( viter) Pour le sport et la minceur, le L-Tartrate est le choix de rfrence

Given that efficacy is related to trough levels, more frequent dosing may be sensible in patients with augmented renal clearance (e.g., 1 gram IV q8hrs rather than 1.5 grams q12hrs)