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AOD-9604 has some clinical trial data, though it has not achieved widespread regulatory approval for weight loss

People who have MTHFR People with MTHFR mutations are advised to supplement with active forms of B12 to support proper methylation

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AOD 9604 has a substantial history of clinical study

For vitamin B12 to be absorbed from the gut, it must bind to a protein called intrinsic factor, which limits how much B12 the gut can take in at one time