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Description
Through a process called S-glutathionylation, glutathione also regulates major DNA repair proteins, such as the Ku70/Ku80 heterodimer used in Non-Homologous End Joining (NHEJ) to repair double-strand breaks
De Loos et al
It catalyzes the reduction of oxidized glutathione (GSSG) to its reduced form, glutathione (GSH), which is a major cellular antioxidant
PMID 31886171
Hallmark gene sets were used for this study
