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Besides enhancing UVA protection, DESM can boost the SPF of high-SPF formulations by up to 5 units
doi: 10.1038/s41575-022-00675-x 40 HeJ.LiuY.OuyangQ.LiR.LiJ.ChenW.et al
One mechanism is through disruption of calcium channels and pumps (e.g., voltage-gated calcium channels (VGCCs), receptor-operated calcium channels, store-operated calcium channels, transient receptor-potential ion channels, and Ca 2+ -ATPase) [28, 37]
Most patients notice initial effects within 1-2 weeks for acute injuries, with progressive improvement over 4-8 weeks
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