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Walker, W

The dihexa half life ensures plasma concentrations fall to negligible levels within six to eight hours, meaning every-other-day dosing creates 40+ hour gaps with zero receptor engagement

This is evident in the rebound of levels in the blood, following discontinuation of a chelator, which highlights two important facts

EMBO J (1997) 16(7):16109.10.1093/emboj/16.7.1610 115 ChinHAraiAWakaoHKamiyamaRMiyasakaNMiuraO

Low GABA has been linked to anxiety, PTSD, sleep issues, and more