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Among different classes of copper ionophores, ES has exhibited acceptable safety and therapeutic efficiency in the clinical practice

They are not recognized as generally regarded as safe (GRAS) substances for dietary supplement use

Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways

[DOI] [PubMed] [Google Scholar] Su LJ, Zhang JH, Gomez H, Murugan R, Hong X, Xu D, Jiang F, Peng ZY

Most significantly, monitoring the GSH level in both hypoxia and recovery status allows for visualization of ventilation-related redox changes
