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Indeed, contrary to the mitochondrial matrix where the aforementioned antioxidant systems restrict their formation, the yeast oxidoreductases Mia40 and Erv1 catalyze disulfide bonds in the IMS, thus forming a mitochondrial disulfide relay process 52

It is estimated that the prevalence of PD in the general population is 0.3%, about 1% in people over 60 years old, and about 3% in people over 80 years old, with an incidence of 818 per 100,000 person-years (Tanner and Goldman, 1996

To view a copy of this licence, visit About this article Cite this article Coden, K.M., Nguyen, D.K.K., Moorhead, R