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Description

Evidence from preclinical and clinical studies highlights their potential in reducing psoriasis area and severity index (PASI) scores, mitigating immune hyperactivity, and enhancing the safety and efficacy of standard therapies

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This review integrates current evidence on how brain peptides contribute to AD pathophysiology, summarizes recent progress in peptide-based therapeutic strategies and delivery platforms, and critically examines the remaining barriers to clinical translation, including bloodbrain barrier penetration, metabolic stability, off-target effects, and the need for biomarker-guided patient stratification