c perfringens has lipase Clostridium alpha toxin Clostridium perfringens - wikidoc
Description
If valproic acid is ineffective in treating a mixed seizure disorder that includes absence, ethosuximide could be used in combination with another AED

ShinSYFaumanEBPetersenAKKrumsiekJSantosRHuangJet al
Aug 2018;72(2):381-390

Inclusion criteria included patients less than 6 months of age prescribed an amino acid formula at the enrollment visit (Visit 1) whose HCPs provided symptom data at Visit 1 and the next visit (Visit 2) at 3 to 6 weeks (n = 104)

But this is only a guide - there is no hard rule set here
