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This discrepancy may be attributed to disease heterogeneity, differences in patient enrollment criteria (e.g., disease stage and progression rate), or genetic factors (37)

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Curr Opin Immunol 22(2):231237 Biswas SK et al (2006) A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)
To this aim, arterial diameter is recorded at baseline and at end-diastole and FMD is calculated as a percentage change from baseline [115]
