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doi: 10.3389/fphar.2024.1407871 177 NielsenFMikkelsenBBNielsenJBAndersenHRGrandjeanP
Bossenmeyer-Pouri C, Smith AD, Lehmann S, Deramecourt V, Sablonnire B, Camadro JM, Pouri G, Kerek R, Helle D, Umoret R, Guant-Rodriguez RM, Rigau V, Gabelle A, Sequeira JM, Quadros EV, Daval JL, Guant J (2019) L., N-homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimers disease and vascular dementia
ROS can also promote the subsequent production of superoxide or hydrogen peroxide from other enzymatic sources that are not normally ROS producers: hydrogen peroxide promotes the uncoupling of endothelial nitric oxide synthase (eNOS) to foster superoxide production rather than nitric oxide production [11, 12] and hydrogen peroxide can convert xanthine oxidoreductase to xanthine oxidase, a superoxide and hydrogen peroxide generator, either by reversible cysteine oxidation or by promoting irreversible proteolysis, [13]
These lipophilic compounds, along with their derivatives, serve as radical-trapping antioxidants, preventing the formation of phospholipid hydroperoxides
doi: 10.1016/j.ijdevneu.2010.03.003
