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In addition to the gut microbiome, cyclopropyl lipids are present in human diets, and have recently become more abundant in meat and dairy products as a result of the widespread introduction of fermented grains (silage) as animal feed during the 20th century 83

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doi: 10.1016/S0140-6736(78)91505-2

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26 While SIRT6 is known to function as a tumor suppressor in some cancers, recent evidence suggests it can act as a tumor promoter in specific contexts, such as in intrahepatic cholangiocarcinoma (iCCA) where it promotes glutamine metabolic reprogramming

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