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But how do they stack up against each other

As mentioned above, Nrf2 ubiquitinated by the Keap1-CUL3 complex under normal conditions is degraded by proteases in the cytoplasm

56 However, more direct assessments of intracellular oxidant stress through measurement of GSSG formation showed no evidence of oxidant stress during the metabolism phase in rats, 64 mice, 65 or mouse hepatocytes

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Orefice L.L., Waterhouse E.G., Partridge J.G., Lalchandani R.R., Vicini S., Xu B

Chronic NF-B activation causes age-related disease by promoting cellular senescence, telomere shortening, and tissue degeneration [205]