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A functional single-cell metabolic survey identifies Elovl1 as a target to enhance CD8 + T cell fitness in solid tumors

Mar 2014;99(3):535-42

SBP-101 (diethyl dihydroxyhomospermine) is a spermine analog that inhibits pancreatic cancer progression by affecting the activity of the polyamine-metabolizing enzyme ODC and depleting intracellular polyamine pools [278]
