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While it is not entirely clear, the expression level of beta(3)-AR RNA, the primary lipolytic receptor in fat cells, was observed to increase in the presence of AOD 9604

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Clinical trials used fixed doses regardless of body weight

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In preclinical mouse models, MOTS-C administration prevented body weight gain of approximately 1520% in high-fat-diet cohorts compared with untreated controls (Lee et al., 2015

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