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In equation (4), R m includes the set of measured reactions

Given that ferroptosis results in cellular rupture and exacerbates inflammation, it remains unclear whether HO-1-induced ferroptosis could establish a positive feedback loop that drives disease progression

Generative models Generative AI in drug discovery is driven by two broad, complementary categories of models: those that are molecular-based and those that are research-based

However, as we documented in our metabolic study on the hippocampus, animals with particular protection induced by preischemia, which manifest a general decrease in neuropathological signs of ischemic injury, showed a lower extent of changes in levels of glutamate, GABA, and glutamine, and a faster metabolic recovery comparable to non-protected animals (Baranovicova et al

dihexa appeared to be extensively distributed outside the central blood compartment and/or bound within the tissues as evidenced by its large volume of distribution (Vd)