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A structural model of the interaction suggests that the active molecule is a hydrolyzed form of PL (hPL) which forms a complex with GSH in the enzyme active site

10.1016/j.jpeds.2009.11.020

doi: 10.1016/j.jssas.2020.08.004 163 SabnamN.BarmanS

& Lu, X

Discussion Synaptic function has been highlighted as key in sustaining cognitive fitness in the face of AD-neuropathology, leading to detailed study into synaptic proteins of AD-dementia and AD-resilient brains 6,8,10,11,12,13