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117 Additionally, considered as a key antioxidative enzyme, NNT is critical for inducing macrophage inflammatory responses 118 and preventing ROS-induced cytotoxicity in T cells exposed to asbestos that can cause a reduction in antitumor immunity

To validate the functional importance of the secondary IGF1-binding site, we introduced Y487A and R488A mutations into IGF1R, and tested their effects on IGF1R activation

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Signal Transduct Target Ther 2:17023

An anatomical T1 MPRAGE image (TE/TR = 3.4/7.3 ms) was acquired for each subject (1 mm isotropic resolution, 256 256 180 matrix, flip angle 8) to aid placement of the VOIs and for co-registration