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and Bertoni, G., 2007

The protective antioxidant mechanisms of RBCs include enzymatic and non-enzymatic antioxidant systems that work together to detoxify the cell from reactive oxygen species (ROS) produced within or outside the cell

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In the early 1980s, several lines of evidence from Etienne, Baulieu, and Robel (69) challenged the central dogma that neuroactive steroids were exclusively synthesized peripherally, demonstrating for the first time that steroids could be synthesized from cholesterol within the CNS