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Keratin, the primary protein of the hair shaft, requires biotin as a cofactor in its synthesis pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] Parisotto EB, Garlet TR, Cavalli VL, Zamoner A, da Rosa JS, Bastos J, Micke GA, Frde TS, Pedrosa RC, Wilhelm Filho D

doi: 10.1161/ATVBAHA.111.240341

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Figures 1B , 3 ), resulting in down-regulation of the hepatic GHR expression, as inferred from reductions in circulating levels of GHBP (59), and decreased GH binding (60)
