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Atherosclerosis occurs primarily in the subendothelial space of the middle and large arteries, where blood flow is disturbed and/or bifurcated (Siasos et al., 2018

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In fact, it has been suggested to be one of the most potent antioxidants because of its ability to scavenge up to 10 reactive oxygen (ROS) and nitrogen species (RNS) with its metabolites compared with most antioxidants, which may only be able to quench a few ROS [16,23,24]

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elegans is a hierarchical process that demands the sequential secretion of protein- and lipid-rich material into the extracellular space after fertilization (Johnston and Dennis, 2012