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Both medications have minimal side effects, mostly involving minor digestive upset or injection site reactions
Studies show that NNMT inhibition by 5-amino-1-methylquinolinium significantly reduces nicotinamide metabolism, increases NAM accumulation, improves NAD+ synthesis efficiency by over 30%, and markedly increases mitochondrial ATP production and cellular energy metabolism

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A., & van den Berg, H

Jun 6 2022;58(6)doi:10.3390/medicina58060770