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The inter-individual variability of the PD parameters was larger than that of the PK parameters
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Lysosomes also serve as signaling hubs to monitor the intracellular levels of nutrients and energy by acting as platforms for the assembly of multiple signaling pathways, such as mammalian target of rapamycin complex 1 (mTORC1) and adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK)
