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How do neuroendocrine and inflammatory pathways interact during stress to contribute to the pathogenesis of depression

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Levy, Michael E

Ocular involvement can also occur, presenting with conjunctivitis, blepharitis, or recurrent chalazia

It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone