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Persistent severe symptoms that interfere with daily activities or lead to dehydration should prompt immediate medical consultation, as medication discontinuation or alternative treatments may be necessary

doi: 10.1242/dmm.029728

(PubMed) Bloos F, Trips E, Nierhaus A, et al

ET-1, through the stimulation of its receptor, mediates inflammation and oxidative stress

However, caffeine may reduce glutathione's effectiveness if taken too close to your supplement
