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Glutathione, a powerful endogenous antioxidant, has been the subject of growing scientific interest over the last decade

Currently, the primary treatment for myocardial infarction is opening blocked vessels to restore blood flow to the ischemic myocardium, which is called reperfusion

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demonstrated in a macrophage-specific IGF-1 Apoe -/- mouse model that macrophage-derived IGF-1 inhibited the expression of chemokine (C-X-C motif) ligand 12 (CXCL12), reduced monocyte recruitment to plaques, and favoured macrophage cholesterol efflux (60)