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Moreover, the molecular signatures of ferroptosis, particularly GPX4 depletion and lipid peroxidation, appear consistently across these disorders, often preceding overt neurodegeneration

Lithocholic acid, a metabolite of the microbiome, increases oxidative stress in breast cancer

Pyroptosis can enhance antitumor immune responses through proinflammatory cytokines such as IL1 and IL18, whereas chronic inflammation induced by pyroptosis may promote tumor progression [155]

(Wu et al., 2021)
