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The bone-brain axis, also known as the brain-bone axis, is a bidirectional regulatory interaction between the brain and bone that can be formed by a variety of methods, according to new research

Additionally, DNA hypermethylation can also disrupt the balance between the active and repressed histone marks of stem-cell-related genes (H3K4me3, H3K27me3) by binding to their cancer-specific promoter and blocking transcription factors from binding, consequently inducing an abnormally silenced state of the gene and chromosome instability [12,70]
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Targeting cancer metabolism to resensitize chemotherapy: Potential development of cancer chemosensitizers from traditional Chinese medicines

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