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Collectively, these results highlight the ability of highly engineered apocynin derivatives to specifically inhibit the NOX2 isoform at its mitochondrial source, while substances such as GKT137831 support the more general NOX inhibition strategy to reduce vascular and tissue-specific ROS in fibrotic diseases and diabetic nephropathy

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Agnew papers, Special Collections, University of Maryland Libraries Saturday Night Massacre Attorney General Elliot Richardson waves to reporters on October 20, 1973, after resigning from office and departing the Justice Department in the midst of the "Saturday Night Massacre." Just 10 days earlier, AG Richardson appeared in federal court to secure the resignation of Vice President Spiro T

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