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Treatment seems to have positive effects on brain structure

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3.7 Trimethylamine-N-oxide in neurodegenerative diseases The recent evidence demonstrates a link between TMAO and several other gut microbial-derived metabolites with neurological diseases (Xu and Wang, 2016)

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(1997): Progressive decrease of cerebral cytochrome C oxidase activity in sparse-fur mice: role of acetyl-L-carnitine in restoring the ammonia-induced cerebral energy depletion