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For example, the level of gene expression in transgenic mice is often quantitatively much different relative to the endogenous level observed in wild type mice

In contrast, larger linear peptides, such as LL-37 and AW1, may exhibit strong antimicrobial activity but often face challenges related to delivery and stability

c , Western blot of HT1080 OE GFP-GPX4 WT and HT1080 OE GFP-GPX4 R152H after treatment with ferroptosis inducers with GPX4 and GAPDH antibodies, with lanes arranged for ferroptosis inducer comparison

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5.4.2 T2DM Many functions of neutrophils, particularly ROS generation, NET formation, bactericidal activity, and chemotaxis, are dysregulated in patients with T2DM (Omori et al., 2008