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[8] Patients with significant alcohol intake or thiamine deficiency also require precaution: chronic heavy alcohol use can deplete thiamine (vitamin B) and taking ALA in the setting of thiamine deficiency has been associated with serious health risks (including a condition resembling Wernickes encephalopathy)

2011 Apr

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Individual Ingredient Comparison: For comparison context, purchasing berberine, cinnamon bark extract, chromium picolinate, gymnema sylvestre, alpha lipoic acid, bitter melon, and banaba leaf as individual supplements from reputable supplement brands would typically cost $40-$80 per month combined, depending on brands and dosages chosen

[DOI] [PubMed] [Google Scholar] 117.Hsu C.C., Huang C.N., Hung Y.C., Yin M.C